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Biology 302: Cell Signaling

Lecture 12 of 18

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"Notice how the receptor changes conformation before the cascade starts..."

14:32
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148 hrs
Citations
1,284
Quiz hits
87%

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Signal transduction begins when the ligand binds and triggers a cascade of intracellular messengers.

14:32 / 21:07
08:41 Receptor activation
12:05 Messenger release
14:32 Cascade starts

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Transcript14:18 - 14:44

The ligand binds to the receptor at the membrane...

The conformational change activates intracellular messengers.

The cell amplifies the signal through a cascade.

AI answer

Signal transduction starts after binding because the receptor must change shape first. That conformational shift triggers the internal messenger pathway and starts the amplification cascade.

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