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Biology 302: Cell Signaling
Lecture 12 of 18
"Notice how the receptor changes conformation before the cascade starts..."
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Signal transduction begins when the ligand binds and triggers a cascade of intracellular messengers.
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The ligand binds to the receptor at the membrane...
The conformational change activates intracellular messengers.
The cell amplifies the signal through a cascade.
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Signal transduction starts after binding because the receptor must change shape first. That conformational shift triggers the internal messenger pathway and starts the amplification cascade.
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